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発表論文-PUBLICATION

Hasegawa A, Tanigawa K, Ohtsuru A, Yabe H, Maeda M, Shigemura J, Ohira T, Tominaga T, Akashi M, Hirohashi N, Ishikawa T, Kamiya K, Shibuya K, Yamashita S, Chhem RK.: Health effects of radiation and other health problems in the aftermath of nuclear accidents, with an emphasis on Fukushima. Lancet. 2015 Aug 1;386(9992):479-88. doi: 10.1016/S0140-6736(15)61106-0. Abstract


Kamiya K, Ozasa K, Akiba S, Niwa O, Kodama K, Takamura N, Zaharieva EK, Kimura Y, Wakeford R.: Long-term effects of radiation exposure on health. Lancet. 2015 Aug 1;386(9992):469-78. doi: 10.1016/S0140-6736(15)61167-9.Abstract


Satoh H, Ohira T, Hosoya M, Sakai A, Watanabe T, Ohtsuru A, Kawasaki Y, Suzuki H, Takahashi A, Kobashi G, Ozasa K, Yasumura S, Yamashita S, Kamiya K, Abe M.: Evacuation after the Fukushima Daiichi Nuclear Power Plant Accident Is a Cause of Diabetes: Results from the Fukushima Health Management Survey. J Diabetes Res. 2015;2015:627390. doi: 10.1155/2015/627390. Epub 2015 May 27.Abstract


Sasatani M, Xu Y, Kawai H, Cao L, Tateishi S, Shimura T, Li J, Iizuka D, Noda A, Hamasaki K, Kusunoki Y, Kamiya K.: RAD18 activates the G2/M checkpoint through DNA damage signaling to maintain genome integrity after ionizing radiation exposure. PLoS One. 2015 Feb 12;10(2):e0117845. doi: 10.1371/journal.pone.0117845. eCollection 2015.Abstract


Asakawa J, Kamiguchi Y, Kamiya K, Nakamura N.: Mutagenic effects of ionizing radiation on immature rat oocytes. Radiat Res. 2014 Oct;182(4):430-4. doi: 10.1667/RR13776.1. Epub 2014 Sep 17.Abstract


Tsuyama N, Mizuno H, Katafuchi A, Abe Y, Kurosu Y, Yoshida M, Kamiya K, Sakai A.: Identification of low-dose responsive metabolites in X-irradiated human B lymphoblastoid cells and fibroblasts. J Radiat Res. 2015 Jan;56(1):46-58. doi: 10.1093/jrr/rru078. Epub 2014 Sep 16.Abstract


Cao L, Kawai H, Sasatani M, Iizuka D, Masuda Y, Inaba T, Suzuki K, Ootsuyama A, Umata T, Kamiya K, Suzuki F.: A novel ATM/TP53/p21-mediated checkpoint only activated by chronic γ-irradiation. PLoS One. 2014 Aug 5;9(8):e104279. doi: 10.1371/journal.pone.0104279. eCollection 2014.Abstract


Shimura T, Hamada N, Sasatani M, Kamiya K, Kunugita N.: Nuclear accumulation of cyclin D1 following long-term fractionated exposures to low-dose ionizing radiation in normal human diploid cells. Cell Cycle. 2014;13(8):1248-55. doi: 10.4161/cc.28139. Epub 2014 Feb 14.Abstract


Tomida J, Itaya A, Shigechi T, Unno J, Uchida E, Ikura M, Masuda Y, Matsuda S, Adachi J, Kobayashi M, Meetei AR, Maehara Y, Yamamoto K, Kamiya K, Matsuura A, Matsuda T, Ikura T, Ishiai M, Takata M.: A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair. Nucleic Acids Res. 2013 Aug;41(14):6930-41. doi: 10.1093/nar/gkt467. Epub 2013 May 30.Abstract


Nagataki S, Takamura N, Kamiya K, Akashi M.: Measurements of individual radiation doses in residents living around the Fukushima Nuclear Power Plant. Radiat Res. 2013 Nov;180(5):439-47. doi: 10.1667/RR13351.1. Epub 2013 Oct 18.Abstract


Yasumura S, Hosoya M, Yamashita S, Kamiya K, Abe M, Akashi M, Kodama K, Ozasa K; Fukushima Health Management Survey Group.: Study protocol for the Fukushima Health Management Survey. J Epidemiol. 2012;22(5):375-83. Epub 2012 Aug 25.Abstract


Masuda Y, Suzuki M, Kawai H, Hishiki A, Hashimoto H, Masutani C, Hishida T, Suzuki F, Kamiya K.:En bloc transfer of polyubiquitin chains to PCNA in vitro is mediated by two different human E2-E3 pairs. Nucleic Acids Res. 2012 Nov 1;40(20):10394-407. doi: 10.1093/nar/gks763. Epub 2012 Aug 16.Abstract


Shi L, Fujioka K, Sun J, Kinomura A, Inaba T, Ikura T, Ohtaki M, Yoshida M, Kodama Y, Livingston GK, Kamiya K, Tashiro S.: A modified system for analyzing ionizing radiation-induced chromosome abnormalities. Radiat Res. 2012 May;177(5):533-8. Epub 2012 Apr 17. doi: 10.1093/nar/gkr805. Epub 2011 Oct 3.Abstract


de Groote FH1, Jansen JG, Masuda Y, Shah DM, Kamiya K, de Wind N, Siegal G.: The Rev1 translesion synthesis polymerase has multiple distinct DNA binding modes. DNA Repair (Amst). 2011 Sep 5;10(9):915-25. doi: 10.1016/j.dnarep.2011.04.033. Epub 2011 Jul 12.Abstract


Masuda Y, Suzuki M, Kawai H, Suzuki F, Kamiya K.: Asymmetric nature of two subunits of RAD18, a RING-type ubiquitin ligase E3, in the human RAD6A-RAD18 ternary complex. Nucleic Acids Res. 2012 Feb;40(3):1065-76. doi: 10.1093/nar/gkr805. Epub 2011 Oct 3.Abstract


Watanabe H, Kominami Y, Gon R, Hayashi M, Nishiki M, Sasaki A, Shiraishi M, Ueda S, Ochiya T, Kamiya K.: Trans-differentiation of a duodenal phenotype on duodenal transplantation of different normal tissues in F344 rats. Hiroshima J Med Sci. 2011 Mar;60(1):1-6.Abstract


Huang QM, Tomida S, Masuda Y, Arima C, Cao K, Kasahara TA, Osada H, Yatabe Y, Akashi T, Kamiya K, Takahashi T, Suzuki M.: Regulation of DNA polymerase POLD4 influences genomic instability in lung cancer. Cancer Res. 2010 Nov 1;70(21):8407-16. doi: 10.1158/0008-5472.CAN-10-0784. Epub 2010 Sep 22.Abstract


Tachibana N, Iwamoto T, Kawamura T, Masuda Y, Mori T, Kamiya K.: Generation and evaluation of an anti-REV1 monoclonal antibody. Hiroshima J Med Sci. 2010 Sep;59(3):51-6.Abstract


Watanabe H, Toyoshima M, Ishikawa M, Kamiya K.: Paternal monoenergetic neutron exposure results in abnormal sperm, and embryonal lethality and transgenerational tumorigenesis in mouse F1 offspring. Oncol Rep. 2010 May;23(5):1351-60.Abstract


Masuda Y, Piao J, Kamiya K.: DNA replication-coupled PCNA mono-ubiquitination and polymerase switching in a human in vitro system. J Mol Biol. 2010 Feb 26;396(3):487-500. doi: 10.1016/j.jmb.2010.01.003. Epub 2010 Jan 11.Abstract


Huang QM, Akashi T, Masuda Y, Kamiya K, Takahashi T, Suzuki M: Roles of POLD4, smallest subunit of DNA polymerase delta, in nuclear structures and genomic stability of human cells. Biochem Biophys Res Commun. 2010 Jan 1;391(1):542-6. doi: 10.1016/j.bbrc.2009.11.094. Epub 2009 Nov 24.Abstract


Piao J, Masuda Y, Kamiya K.: Specific amino acid residues are involved in substrate discrimination and template binding of human REV1 protein. Biochem Biophys Res Commun. 2010 Feb 5;392(2):140-4. doi: 10.1016/j.bbrc.2009.12.167. Epub 2010 Jan 6.Abstract


Fukuda H, Takamura-Enya T, Masuda Y, Nohmi T, Seki C, Kamiya K, Sugimura T, Masutani C, Hanaoka F, Nakagama H.: Translesional DNA synthesis through a C8-guanyl adduct of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Vitro: REV1 inserts dC opposite the lesion, and DNA polymerase kappa potentially catalyzes extension reaction from the 3'-dC terminus. J Biol Chem. 2009 Sep 18;284(38):25585-92. doi: 10.1074/jbc.M109.037259. Epub 2009 Jul 23.Abstract


Uehara Y, Ikehata H, Komura J, Ito A, Ogata M, Itoh T, Hirayama R, Furusawa Y, Ando K, Paunesku T, Woloschak GE, Komatsu K, Matsuura S, Ikura T, Kamiya K, Ono T.: Absence of Ku70 gene obliterates X-ray-induced lacZ mutagenesis of small deletions in mouse tissues. Radiat Res. 2008 Aug;170(2):216-23. doi: 10.1667/RR1283.1.Abstract


Tomida J, Masuda Y, Hiroaki H, Ishikawa T, Song I, Tsurimoto T, Tateishi S, Shiomi T, Kamei Y, Kim J, Kamiya K, Vaziri C, Ohmori H, Todo T.: DNA damage-induced ubiquitylation of RFC2 subunit of replication factor C complex.J Biol Chem. 2008 Apr 4;283(14):9071-9. doi: 10.1074/jbc.M709835200. Epub 2008 Feb 1.Abstract


Gu Y, Masuda Y, Kamiya K.: Biochemical analysis of human PIF1 helicase and functions of its N-terminal domain. Nucleic Acids Res. 2008 Nov;36(19):6295-308. doi: 10.1093/nar/gkn609. Epub 2008 Oct 3.Abstract


Watanabe H, Kamiya K.: The induction of insulinomas by X-irradiation to the gastric region in Otsuka Long-Evans Tokushima Fatty rats. Oncol Rep. 2008 Apr;19(4):987-91.Abstract


Ikura T, Tashiro S, Kakino A, Shima H, Jacob N, Amunugama R, Yoder K, Izumi S, Kuraoka I, Tanaka K, Kimura H, Ikura M, Nishikubo S, Ito T, Muto A, Miyagawa K, Takeda S, Fishel R, Igarashi K, Kamiya K.: DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics. Mol Cell Biol. 2007 Oct;27(20):7028-40. Epub 2007 Aug 20.Abstract


Masuda Y, Suzuki M, Piao J, Gu Y, Tsurimoto T, Kamiya K.: Dynamics of human replication factors in the elongation phase of DNA replication. Nucleic Acids Res. 2007;35(20):6904-16. Epub 2007 Oct 11.Abstract


Watanabe H, Kashimoto N, Kajimura J, Ishikawa M, Kamiya K.: Tumor induction by monoenergetic neutrons in B6C3F1 mice. J Radiat Res. 2007 May;48(3):205-10. Epub 2007 Apr 19.Abstract


Watanabe H, Ochiya T, Ueda S, Kominami Y, Gon R, Nishiki M, Hayashi M, Sasaki A, Shiraishi M, Kashimoto N, Myojin Y, Kamiya K.: Differentiation of a hepatic phenotype after heterotropic transplantation of heart, kidney, brain, and skin tissues into liver in F344 rats. Biochem Biophys Res Commun. 2007 Mar 23;354(4):841-5. Epub 2007 Jan 22.Abstract


Watanabe H, Kashimoto N, Kajimura J, Kamiya K.: A miso (Japanese soybean paste) diet conferred greater protection against hypertension than a sodium chloride diet in Dahl salt-sensitive rats. Hypertens Res. 2006 Sep;29(9):731-8.Abstract


Kashimoto N, Hayama M, Kamiya K, Watanabe H.: Inhibitory effect of a water-soluble extract from the culture medium of Ganoderma lucidum (Rei-shi) mycelia on the development of pulmonary adenocarcinoma induced by N-nitrosobis (2-hydroxypropyl) amine in Wistar rats. Oncol Rep. 2006 Dec;16(6):1181-7.Abstract


Masuda, Y., Kamiya, K.: Role of single stranded DNA in targeting REV1 to primer termini. J. Biol. Chem., Aug 25;281(34):24314-24321, 2006.Abstract


Kamath-Loeb, A., Masuda, Y., Hanaoka, F., Loeb L.A.: The First US-Japan Meeting on Error-Prone DNA Synthesis, Maui, Hawaii, December 20 - 21, 2004. DNA Repair, Jun; 4(6): 740-747, 2005.Abstract


Wang, A., Ikura, T., Eto, K. Ota, M.S.: Dynamic interaction of p220NPAT and CBP/p300 promotes S-phase entry.Biochem. Biophys. Res. Commun., Dec 24;325(4):1509-1516, 2004. Abstract


Mochizuki, H., Matsubara, A., Teishima, J., Mutaguchi, K., Yasumoto, H., Dahiya, R., Usui, T., Kamiya, K.: Interaction of ligand-receptor system between stromal-cell-derived factor-1 and CXC chemokine receptor 4 in human prostate cancer: a possible predictor of metastasis. Biochem. Biophys. Res. Commun., Jul 30; 320(3):656-663, 2004.Abstract


Guo, C., Fischhaber, P.L., Luk-Paszyc, M.J., Masuda, Y., Zhou, J., Kamiya, K., Kisker, C., Friedberg, E.C.: Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis. EMBO J., Dec 15, 22 (24), 6621-6630, 2003.Abstract


Masuda, Y., Ohmae, M., Masuda, K., Kamiya, K.: Structure and enzymatic properties of a stable complex of the human REV1 and REV7 proteins. J. Biol. Chem., Apr 4;278(14):12356-12360, 2003.Abstract


Ikura, T., Ogryzko, V.V.: Chromatin dynamics and DNA repair. Front. Biosci., Jan 1, 8, 149-155, 2003.Abstract


Masuda, Y., Kamiya, K.: Analysis of translesion DNA synthesis activity of the human REV1 protein, what is a key player in radiation-induced mutagenesis. Proceedings of the International Symposium on Biological Effects of Low Dose Radiation: Molecular Mechanisms for Radiation-induced Cellular Response and Cancer Development, pp.250-257, (ed by Tanaka, K., Takabatake, K., Fujikawa, T., Matsumoto, T., Sato, F.), Aomori, 2002.


Kamiya, K., Sumii, M., Masuda, Y., Ikura, T., Koike, N., Takahashi, M., Teishima, J.: Genetic analysis of radiation-induced mouse hepatomas. Proceedings of International Symposium on Radiation and Homeostasis (Ed. by Sugahara, T.), Elsevier, Amsterdam, Netherland, 151-156, 2002.


Masuda, Y., and Kamiya, K.: Biochemical properties of the human REV1 protein. FEBS Letters, Jun 5;520 :88-92, 2002.Abstract


Sugaya, Y., Ihara, K., Masuda, Y., Ohtsubo, E., Maki, H.: Hyper-processive and slower DNA chain elongation catalysed by DNA polymerase III holoenzyme purified from the dnaE173 mutator mutant of Escherichia coli. Genes Cells Apr;7(4):385-99, 2002.


Masuda, Y., Takahashi, M., Fukuda, S., Sumii, M., Kamiya, K.: Mechanisms of dCMP transferase reactions catalyzed by mouse Rev1 protein. J. Biol. Chem., Jan 25; 277(4): 3040-3046, 2002.Abstract


Takahashi, K., Nuckolls, G.H., Takahashi, I., Nonaka, K., Nagata, M., Ikura, T., Slavkin, H.C., Shum, L.: Msx2 is a repressor of chondrogenic differentiation in migratory cranial neural crest cells. Dev. Dyn., Oct;222(2):252-262, 2001.


Ayres, J.A., Shum, L., Akarsu, A.N., Dashner, R., Takahashi, K., Ikura, T., Slavkin, H.C., Nuckolls, G.H.: DACH: genomic characterization, evaluation as a candidate for postaxial polydactyly type A2, and developmental expression pattern of the mouse homologue. Genomics, Sep; 77(1-2): 18-26, 2001.


Fuchs, M., Gerber, J., Drapkin, R., Sif, S., Ikura, T., Ogryzko, V., Lane, W.S., Nakatani, Y., Livingston, D.M.: The p400 complex is an essential E1A transformation target. Cell, Aug 10; 106(3): 297-307, 2001.


Masuda, Y., Takahashi, M., Tsunekuni, N., Minami, T., Sumii, M., Miyagawa, K., Kamiya, K.: Deoxycytidyl transferase activity of the human REV1 protein is closely associated with the conserved polymerase domain. J. Biol. Chem., May 4; 276(18):15051-15058, 2001.Abstract


Fukuda, S., Sumii, M., Masuda, Y., Takahashi, M., Koike, N., Teishima, J., Yasumoto, H., Itamoto, T., Asahara, T., Dohi, K., Kamiya, K.: Murine and human SDF2L1 is an endoplasmic reticulum stress-inducible gene and encodes a new member of the Pmt/rt protein family. Biochem. Biophys. Res. Commun., Jan 12;280(1):407-414, 2001.Abstract


Ogawa, K. , Osanai, M. , Obata, M. , Ishizaki, K. , Kamiya, K.: Gain of chromosomes 15 and 19 is frequent in both mouse hepatocellular carcinoma cell lines and primary tumors, but loss of chromosomes 4 and 12 is detected only in the cell lines. Carcinogenesis; 20, 2083-2088, 1999.


Kamiya, K., Higgins, P, D., Tanner, M, A., Gould, M, N., and Clifton, K, H.: Kinetics of Mammary Clonogenic Cells and Rat Mammary Cancer Induction by X-rays or Fission Neutrons. J. Radiat. Res. 40 Suppl, 128-137, 1999.


Kamiya, K., Nitta, Y. , and Gould, M, N.: Susceptibility to radiation-induced mammary carcinoma in genetically resistant Copenhagen rats. Proceedings of International Symposium on Biological Effects of Low Dose Radiation, pp.151-158, (ed by Sato, F., Yamada, Y., Onodera, I.), Aomori, 1999.


Hiramoto, T., Nakanishi, T., Sumiyoshi, T., Fukuda, T., Matsuura, S., Tauchi, H., Komatsu, K., Shibasaki, Y., Inui,H., Watatani, M., Yasutomi, M., Sumii, M., Kajiyama, G., Kamada, N., Miyagawa, K., Kamiya, K.: Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer. Oncogene,18:3422-3426, 1999.


Matsuda, M., Miyagawa, K., Takahashi, M, Fukuda, T., Kataoka, T., Asahara, T., Inui, H., Watatani, M., Yasutomi, M., Kamada, N., Dohi, K., Kamiya, K: Mutations in the RAD54 recombination gene in primary cancers. Oncogene, 18:3427-3430, 1999 .


Miyagawa, K., Hayashi, Y., Fukuda, T., Mitani, K., Hirai, H., Kamiya, K.: Mutations of the WT1 gene in childhood non-lymphoid hematological malignancies. Genes Chromo. Cancer, 25:176-183, 1999.


Kamiya, K., Gould, M.N., Clifton, K.H.: Quantitative studies of ductal versus alveolar differentiation from rat mammary clonogens. Proc. Soc. Exp. Biol. Med., 219: 217-225, 1998.


Shimokado, K., Watanabe, H., Sumii, M., Miyagawa, K., Kamiya, K., Dohi, K. and Niwa, O.: p53 gene mutation and loss of heterozygosity of chromosome 11 in methylcholanthrene-induced mouse sarcomas. Jpn. J. Cancer Res., 89: 269-277, 1998.